2025 ASBMR Symposium on Musculoskeletal Impact of Immune and Skeletal Cells Crosstalk: Bench to Bedside
Thursday, September 4, 2025
The 2025 ASBMR Symposium will be held on Thursday, September 4, 2025, one day prior the 2025 Annual Meeting, at the Seattle Convention Center in Seattle, Washington, USA. Organized by Laura Calvi, M.D. and Natalie Sims, Ph.D., the goal of this topical meeting is to to discuss novel interactions between immune cell populations and skeletal cells that impact musculoskeletal health, including pathogenesis of rheumatologic, infectious and age-associated disorders, in order to envision future therapeutic, analytical and diagnostic tools.
Questions? Contact the ASBMR Business office by email at asbmr@asbmr.org or by phone at +1 (202) 367-1161.
Program
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Continental Breakfast |
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8:30 am - 10:15 am
Session 1: Reciprocal Interactions of Skeletal and Immune Cells
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8:30 am - 8:45 am
Introduction & Overview - Laura Calvi & Natalie Sims
8:45 am - 9:10 am
Neutrophils/Oncostatin M - Natalie Sims
9:10 am - 9:35 am
Reciprocal suppression between TGFβ signaling and TNF stimulation finetunes the macrophage inflammatory response - Baohong Zhao
9:35 am - 10:00 am
Osteolineage cell efferocytosis links skeletal and hematopoietic homeostasis - Laura Calvi
10:00 am - 10:15 am
Macrophage Efferocytosis impacts the skeleton - Lena Batoon
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10:15 am - 10:30 am
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Break |
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10:30 am - 12:00 pm
Session 2: Musculoskeletal Impact of Immune Cells
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10:30 am - 10:55 am
TBD
10:55 am - 11:20 am
Role of a tubular lysosomal network in osteoclast function - Nathan Pavlos
11:20 am - 11:45 am
TNF- induced activation of Schnurri 3 in osteoblasts contributes to systemic and articular bone loss by suppressing bone formation and enhancing osteoclast development - Jae-Hyuck Shim
11:45 am - 12:00 pm
Talk from submitted abstracts
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12:00 pm - 1:00 pm
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Lunch & Poster Viewing
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1:00 pm - 2:30 pm
Session 3: Pathogenesis of Cancer and Age-associated Disorders
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1:00 pm - 1:25 pm
DKK1 creates a tumor-supporting environment through the suppression of NK cells during breast cancer progression - Roberta Faccio
1:25 pm - 1:50 pm
Neutrophil anti-tumor responses against bone metastatic prostate cancer: mechanisms and therapeutic opportunities - Leah Cook
1:50 pm - 2:15 pm
Clonal hematopoiesis and its impact on the aging osteo-hematopoietic (CHIP, MDS and its implication on bone health) - Lorenz Hofbauer
2:15 pm - 2:30 pm
Talk from submitted abstracts
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2:30 pm - 3:00 pm
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Break
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3:00 pm - 4:30 pm
Session 4: Future Therapeutic, Analytical and Diagnostic Tools
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3:00 pm - 3:25 pm
Acod1 and itaconate are crucial regulators of osteoclast differentiation and bone loss in inflammatory arthritis - Aline Bozec
3:25 pm - 3:50 pm
Role of regulatory T cells in fracture repair - TBD
3:50 pm - 4:15 pm
Translation opportunities in osteomyelitis - Edward Schwarz
4:15 pm - 4:30 pm
Talk from submitted abstracts
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4:30 pm - 6:00 pm
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Combined Pre-Meeting Reception & Poster Viewing
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